If you are interested in tracking TR101 P2 errors for Sources of a specific client but not for others, you can create two different Events Profiles, one with TR101 P2 tracking enabled and the other with it disabled. You can then apply the appropriate Events Profile to each of your Sources.
If you want to set different GPU thresholds for broadcasters hosted on different types of machines, you can create different Events Profiles with different thresholds for broadcaster GPU usage.
If you don’t want to send any notifications for errors on a specific group of resources, you can create an Events Profile in which Notifications are disabled for all rules and apply that profile to the desired resources.